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Education

Education is paramount to the CannaSafe philosophy. The full medicinal potential of cannabis can be unlocked with a comprehensive understanding of the different components in the cannabis plant and how to best optimize their ability to work in concert.

Cannabis

Cannabinoids and the Endocannabinoid System

The endocannabinoid system is a collection of endogenous cannabinoid receptors found throughout the body that effect mood, pain-sensations, appetite, and memory. The endocannabinoid system is linked to many of the body’s other life support structure, such as the nervous system and the immune system. The three most well-studied cannabinoid receptors are the CB-1, CB-2, and 2-AG receptors. Different cannabinoids interact with different receptors in different ways. ∆9-THC interacts mainly with the CB-1 receptor that is primary found in the brain and nervous system, whereas ∆8-THC interacts with both the  CB-1 and CB-2 receptors. By dividing itself between the two receptors, ∆8-THC lessens it potential psycho-activity.

The potential medicinal effects that can be brought about by cannabis are not restricted to the most well-know cannabinoids.

endocannabinoids

Terpenoids and the Entourage Effect

Terpenes are known for their palpable flavors and aromas, but terpenes are not restricted to they interaction with your olfactory senses. Terpenes can interact with cannabinoids for what is known as entourage. This effect, more formally described a synergy, is the exponential potency of combined chemicals versus the effectiveness of the compounds individuals.

Residual Solvent Screening

The introduction of concentrates and vape-pens to a once completely “natural” industry has some in a state of alarm. However, customers and manufactures have resources that can ensure the safety of  their concentrates by getting residual solvent screening. The concentration or extraction process can follow many different paths; between extraction, concentrating, winterizing, and diluting, the cannabis plant undergoes many steps where it comes in contact with substances which some may not be comfortable.

The standard currently accepted, and being used as a template for residual solvent standards is USP 467. In this piece of legislation, put forth by the US Pharmacopeial Convention in partnership with the Food and Drug Administration (FDA), safety limits for Class One, Class Two, and Class Three solvents was outlined. CannaSafe analytics prides itself on staying current with legislation and how it impacts the client, patient, or consumer. After receiving residual solvent screening via GC-FID HEADSPACE, the customer is welcome to consultation regarding compliance with USP 467.

Microbial Testing

Patients struggling with a variety of cancers, and other immune disorders, have found solace in the medicinal effects of cannabis. However, potential risks from microbial contamination can tarnish the potential medicinal value of the cannabis plant.

Definitions

Delta-9 Tetrahydrocannabinol – THC

Delta-9-tetrahydrocannabinol (Delta-9-THC) is the primary psychoactive ingredient in cannabis. It induces feelings of euphoria and relaxation, stress relief and pleasure. THC contains antiemetic properties which are effective against vomiting and nausea and also acts as a pain reliever..

Cannabidiol – CBD

CBD is a non-psychoactive cannabinoid, meaning it will not get you high and in fact will temper the effects of THC. It is an anxiolytic used for treatment of anxiety and its related psychological and physical symptoms which make it useful in treatment of anxiety disorders. CBD contains antipsychotic properties. Strains with high CBD content include Harlequin, Catatonic and Avidekel..

Cannabichromene – CBC

CBC has shown to be an anti-inflammatory and antibiotic that can destroy or inhibit the growth of other microorganisms. Antibiotics are widely used in the prevention and treatment of infectious diseases..

Cannabigerol – CBG

CBG is believed to be the biogenetic precursor of CBD, THC and CBC. Research has shown that it also behaves as a potent alpha(2)-adrenoceptor agonist which causes sedation.  Additionally, CBG has been compared in both structure and antibacterial properties to grifolin,  an antibiotic which makes it effective against fungal infections.

 

CBG molecule.